I have a question concerning the opposing roles of ampk and mtor in protein synthesis.
First, I find this confusing, as exercise increases both ampk and mtor, yet they have opposite effects on protein synthesis. In at least on theory of muscular hypertrophy, protein synthesis is acutely suppressed during exercise (presumably from the increased ampk). Insulin sensitivity is increased from resistance training for some time after, again presumably in part from increased ampk levels. So why doesn’t the increased ampk levels continue to suppress protein synthesis after training? Do they fall below a certain threshold?
More importantly, why would it be a good idea to take a supplement like Indigo (or any drug or supplement, for example, that would increase ampk) at the same time you’re using Micro-PA for increased protein synthesis?
Thanks for the much needed clarification.